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Telehealth / primary care
4.0
Sesame
Best for uninsured or high-deductible readers who want an upfront price for a visit, or a lower-fee brand-only GLP-1 program.
Sesame is the honest budget option: transparent per-visit cash prices, clinicians in every state, and a weight-loss program that sells brand-name GLP-1s only. It does not bill insurance, so insured readers pay out of pocket for the visit.
Telehealth visits from $34; weight-loss program $99/mo or $59/mo annual
What this section is for
An online prescriber works under two sets of rules, and both matter more than any company's marketing. State medical boards decide what counts as a legitimate evaluation and where a clinician must be licensed; federal law decides which drugs may be prescribed without an in-person visit at all. This pillar collects the guides that read those rules from their sources, and the GLP-1 program directory applies them program by program, with each program's price and legal entity read from its own pages and dated.
Where the visit legally happens
The practice of medicine happens where the patient is, so a prescriber must be licensed in the state where you are at the time of the visit. State boards require a documented evaluation and history before any prescription, and the Federation of State Medical Boards' 2022 policy is explicit that prescribing from a static questionnaire alone is not acceptable. GLP-1 telehealth: how online prescribing works follows a visit from intake to pharmacy against those rules, and explains why semaglutide and tirzepatide, which are not controlled substances, are easier to prescribe online than testosterone, which is.
The federal rule with an expiry date
Since 2008 the Ryan Haight Act has required at least one in-person medical evaluation before a clinician may prescribe a controlled substance remotely. A DEA and HHS rule has suspended that requirement without a break since 2020, most recently through a fourth temporary extension effective January 1, 2026 through December 31, 2026, under which a DEA-registered practitioner may prescribe Schedule II to V medications over audio-video telemedicine with no prior in-person visit. Testosterone is Schedule III and amphetamine is Schedule II, so online TRT and ADHD prescriptions depend on that rule and on what replaces it. What an online prescriber can legally prescribe you reads the Federal Register notice and the statute it suspends.
What to check before you pay
Four things, all of which the directory prints for each program: the legal entity behind the site (a program that does not disclose one is not listed as qualifying), the medication price separate from the membership fee, whether the medication is the FDA-approved product or a compounded copy, and how the prescriber evaluates you. On the last point, what the FDA says about compounded GLP-1s matters: compounded semaglutide and tirzepatide are not FDA-approved, the FDA does not review them for safety, effectiveness or quality before they are marketed, and since September 9, 2025 the agency has sent telehealth companies 113 warning letters over how they market compounded GLP-1s. That total is our count of three FDA rounds (58, 30 and 25 letters); the FDA publishes the letters individually and states no running total. Where we have a commercial relationship with a program, the page says so and the vetting record is public.
Frequently asked questions
Can an online doctor prescribe testosterone?
Yes, through December 31, 2026, under the DEA and HHS telemedicine rule, which allows a DEA-registered practitioner to prescribe Schedule II to V drugs over audio-video telemedicine without a prior in-person visit. Without that rule, the Ryan Haight Act requires at least one in-person medical evaluation before a controlled substance is prescribed remotely. The prescriber must also be licensed in the state where you are.
Is a questionnaire-only visit acceptable?
Not from a static questionnaire alone. The FSMB's 2022 telemedicine policy says diagnosis or prescribing based solely on static online questionnaires is not acceptable, and that a physician using an adaptive questionnaire must be able to ask follow-up questions. Programs in our directory are labeled by the prescriber contact they actually offer: an online questionnaire with no live visit, a video visit, a questionnaire with a video visit when required, or no prescriber at all.