Choose your path
Trimi, SHED, Bodybuilding Health+ and Sesame pay us a commission when a reader signs up through our links on other pages of this site. The price links here are untracked, so we earn nothing when you follow one, and no seller paid to appear in this table or to be placed where it is. These are sellers we have reviewed, not a survey of the market: other compounded sellers exist that we have not checked. Here is how we pick.
Every option over 12 months
Medication cost only; add program fees from the table below if you need online prescribing. Ranges run from the lowest price the seller publishes to the highest.
| Option | Total, 12 mo | Per month | Notes |
|---|---|---|---|
|
Wegovy pen (brand, self-pay) NovoCare Pharmacy · 2026-08-19 |
$3,888–$4,388 | $324–$366 | $199/mo for the first two months (new patients), then $349, or $399 for Wegovy HD. |
|
Wegovy tablets (brand, self-pay) NovoCare Pharmacy · 2026-08-19 |
$1,788–$3,588 | $149–$299 | $149 to $299/mo depending on dose. |
|
Zepbound (brand, self-pay) LillyDirect · 2026-08-19 |
$5,188 | $432 | $299 (2.5 mg) month one, $399 (5 mg) month two, then $449 for 7.5 to 15 mg refilled within 45 days; a late refill reprices to $499 to $699. |
|
Foundayo (brand, self-pay) LillyDirect · 2026-08-19 |
$1,788–$3,588 | $149–$299 | $149 to $299/mo depending on dose. |
|
Compounded semaglutide, Trimi (all-in) Trimi · 2026-08-19 |
$1,188–$2,100 | $99–$175 | $175 month to month down to $99/mo on a 12-month prepay; prescribing included. Not an FDA-approved product. |
|
Compounded semaglutide, SHED (all-in) SHED · 2026-09-18 |
$1,908–$2,388 | $159–$199 | $199/mo month to month, $179/mo on a 6-month plan, $159/mo on 12 months, from Shed's own plan table. Every program carries a two-month minimum (terms 11.1), so a one-month total is not purchasable. Shed's weight-loss category card lists the same drug at 'Starting at $249/month', which its product page contradicts. Not an FDA-approved product. |
|
Compounded semaglutide, Bodybuilding Health+ (all-in) Bodybuilding Health+ · 2026-09-18 |
$1,704–$3,248 | $142–$271 | Re-read 2026-09-18: $141.50/mo on a 12-month prepay ($158 on 6 months, $159.33 on 3), which this calculator rounds up to $142 so it never understates a month. Month to month: $179 for the first month under a limited-time promotion, with $279 struck through beside it; the site does not state the price after month one, so the high end of our arithmetic uses $279 from month two. All sales final. Not an FDA-approved product. |
Program fees, if you want online prescribing
A program writes the prescription and handles insurance paperwork; the medication above is still billed separately on brand paths.
| Program | Fee schedule |
|---|---|
| Ro Body, month to month | $39 first month (refunded if not eligible), then $149/mo. |
| Ro Body, annual prepay | $39 first month, then the $74/mo rate that requires a prepaid annual plan. |
| Sesame weight-loss program, monthly | $99/mo; brand medication only. |
| Sesame weight-loss program, annual rate | $59/mo on an annual plan; brand medication only. |
We have reviewed these programs: BetterHelp, Bodybuilding Health+, Everlywell, FullWell, Ro Body, Sesame, SHED, Trimi. Side by side: the ranked comparison.
What this calculator does not know
Insurance. With commercial coverage and a manufacturer savings card, brand GLP-1s can drop to $25 a month; Medicare Part D still cannot cover drugs used solely for weight loss. Our coverage guide walks through it. Prices here are the sellers' posted self-pay rates on the date shown; they change, and we re-check them when we update this page.