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Biomarker library / Blood counts

Hemoglobin (Hb)

Also called hemoglobin, Hgb, anemia blood test

Hemoglobin is the oxygen-carrying protein in red blood cells, measured as part of a complete blood count. A low value defines anemia; the cutoffs below are the WHO 2024 guideline values for adults 15 to 65.

Written by the VitalDecades editorial team Reviewed by the editorial review process Updated

01  /  Reference ranges

What counts as normal

Scale in g/dL. Cut points from the sources listed below.

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Population Adult men 15 to 65 (male)
Category No anemia
Range 13 or higher g/dL 130 g/L and above (WHO 5th-percentile cutoff).
Population Adult men 15 to 65 (male)
Category Mild anemia
Range 11 to 12.9 g/dL 110 to 129 g/L.
Population Non-pregnant women 15 to 65 (female)
Category No anemia
Range 12 or higher g/dL 120 g/L and above (WHO 5th-percentile cutoff).
Population Non-pregnant women 15 to 65 (female)
Category Mild anemia
Range 11 to 11.9 g/dL 110 to 119 g/L.
Population Adults 15 to 65
Category Moderate anemia
Range 8 to 10.9 g/dL 80 to 109 g/L, both sexes.
Population Adults 15 to 65
Category Severe anemia
Range under 8 g/dL Under 80 g/L; urgent evaluation.

Normal vs optimal

The WHO cutoffs are the 5th percentile of healthy populations: they define anemia, not an optimal zone. Values modestly above the cutoff are normal. WHO adjusts readings downward for smoking and altitude, both of which raise hemoglobin; a persistently high value is a clinical conversation, not a target, and this page's sources do not cover its workup.

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02  /  Why it matters

What the number tells you

Anemia is one of the most common lab findings in the world, and hemoglobin is how it is defined: below 13.0 g/dL (130 g/L) in men and below 12.0 g/dL (120 g/L) in non-pregnant women, per the WHO 2024 guideline. The severity grades change the urgency: mild anemia is usually an outpatient iron question; severe anemia is an urgent evaluation. The cause matters more than the number, and iron deficiency (check ferritin) is the most common one.

03  /  In practice

Testing and what moves it

When it is tested

  • On any complete blood count: routine physicals, fatigue evaluations, pre-operative checks.
  • With heavy menstrual bleeding, gastrointestinal symptoms, or a vegetarian or vegan diet plus symptoms.
  • A low result leads to ferritin, B12 and sometimes kidney testing to find the cause.

What raises it

  • Smoking and living at altitude: WHO's 2024 guideline publishes adjustments for both (for example, subtract 8 g/L at 1,000 to 1,499 m, and 3 to 6 g/L for smokers by cigarettes per day).
  • Dehydration raises the concentration without adding red cells.

What lowers it

  • Iron deficiency (blood loss, low intake, poor absorption), B12 or folate deficiency, chronic kidney disease, chronic inflammation, blood disorders.
  • Pregnancy lowers it physiologically; pregnancy cutoffs differ by trimester.

04  /  Related

Frequently asked questions

What hemoglobin level means anemia?

Below 13.0 g/dL (130 g/L) in adult men and below 12.0 g/dL (120 g/L) in non-pregnant women, per the WHO 2024 guideline. Pregnancy uses different, trimester-specific cutoffs.

What should I test after a low hemoglobin?

Usually ferritin first, because iron deficiency is the most common cause; then B12 and, depending on the picture, kidney function and stool testing for blood loss. Treating anemia without finding its cause misses the point of the test.

Is high hemoglobin good?

No; the WHO cutoffs mark anemia, not a ladder to climb. WHO's guideline adjusts readings downward for smoking and altitude, both of which raise hemoglobin. A persistently high value belongs with a clinician; this page's sources do not cover its workup.

How we reviewed this page

Every figure on this page is tied to the document that sets it, with that document's own date. We read each source's title and text against the specific claim before publishing, and we re-check the sources when we update the page. Last checked . How we verify.

Sources (1)
  1. WHO Guideline on haemoglobin cutoffs to define anaemia (2024) 2024-03-05