01 / Reference ranges
What counts as normal
Normal vs optimal
Lab "normal" ranges for ferritin are wide and vary by sex and lab. The WHO thresholds below are not a normal range; they are the cutoffs for iron deficiency and for risk of iron overload. A ferritin of 20 µg/L is above the deficiency cutoff and can still be low-normal iron stores; interpretation depends on symptoms, hemoglobin and inflammation.
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02 / Why it matters
What the number tells you
Low ferritin means depleted iron stores, the stage before and during iron-deficiency anemia: fatigue, reduced exercise capacity, hair shedding and restless legs are common complaints. The catch is that ferritin is also an acute-phase protein: infection or inflammation raises it, which can hide a real deficiency. That is why the WHO sets a higher deficiency cutoff (under 70 µg/L) when inflammation is present and advises checking an inflammation marker alongside ferritin.
03 / In practice
Testing and what moves it
When it is tested
- Fatigue, anemia on a blood count, heavy menstrual bleeding, restless legs, notable hair shedding, or a vegetarian or vegan diet with symptoms.
- With a marker of inflammation (such as CRP) when infection or inflammation is possible, per WHO.
- Repeated high results, especially with a family history, prompt evaluation for iron overload (hereditary hemochromatosis).
What raises it
- Infection and inflammation of any cause (ferritin is an acute-phase reactant), liver disease, alcohol.
- True iron overload: hereditary hemochromatosis, repeated transfusions, high-dose iron supplementation.
What lowers it
- Blood loss (menstrual, gastrointestinal), pregnancy demands, low dietary iron or poor absorption (celiac disease, bariatric surgery).
- Frequent blood donation.
04 / Related
Read next
Frequently asked questions
What ferritin level means iron deficiency?
Under 15 µg/L in apparently healthy adults, per the WHO 2020 guideline. With infection or inflammation the cutoff rises to under 70 µg/L, because inflammation pushes ferritin up and can mask a deficiency.
Why do women ask about ferritin and hair loss?
Iron deficiency is a recognized contributor to diffuse hair shedding, and menstruating women are the group most likely to run low iron stores. A ferritin under the WHO cutoff with hair shedding is worth treating and re-testing; a mid-range ferritin usually is not the explanation.
My ferritin is high. Do I have hemochromatosis?
Not necessarily; infection, inflammation, liver disease and alcohol all raise ferritin. WHO flags risk of iron overload above 150 µg/L in healthy women and 200 µg/L in healthy men; the next step is usually transferrin saturation and, if that is high too, genetic testing.