Who this is for
Every adult 19 and older is covered by both schedules. For readers in their 30s through their 60s the rows that change with age are pneumococcal and shingles, which both start at 50; RSV, which starts at 50 with risk factors and at 75 for everyone; and HPV, where routine vaccination stops at 26 and becomes a discussion between 27 and 45.
Everything else on the adult schedule is either annual (influenza, COVID-19), on a fixed interval (a tetanus, diphtheria and pertussis booster every 10 years), or condition-dependent. The medical-condition table, not the age table, is what decides several of them: chronic heart, lung, liver or kidney disease, diabetes, immunocompromise, pregnancy and smoking all move rows earlier.
Read the disagreement note before you take either schedule as settled. The federal schedule is currently the one a court ordered restored, not the one the agency last published.
Where the recommendations diverge
- CDC / ACIP 19 and older
- CDC / ACIP Not age-bounded Not age-bounded
- CDC / ACIP 50 and older
- CDC / ACIP 50 and older
- CDC / ACIP 19 and older
- CDC / ACIP 27 to 45
- AAFP Not age-bounded Not age-bounded
- AAFP Not age-bounded Not age-bounded
- AAFP 50 and older
Pursuant to the preliminary order issued on March 16, 2026, in American Academy of Pediatrics et al. v. Kennedy et al. ... the July 2, 2025 immunization schedule (as amended on April 27, 2026 to add the ACIP's April 2025 RSV recommendation as adopted by HHS) posted here is the current CDC Adult Immunization Schedule by Age for Healthcare Professionals.
Our note: The ellipsis omits the order's own description of what it stayed: the case number, and the clause "which stayed all votes taken by the ACIP during its June, September and December 2025 meetings, and further stayed the Acting CDC Director's January 5, 2026 Decision Memo revising the CDC's childhood immunization schedule". DATE: the page's own stamp is July 2, 2025, which is the schedule in force; the April 27, 2026 amendment is named inside the quote rather than used as the row date, because the page dates itself to July 2, 2025.
CDC recommends vaccination every 10 years for all adults to maintain protection against tetanus. Once an adult has received a dose of Tdap, administer Td or Tdap for their booster doses.
Our note: No ages are attached to this recommendation on the page, which says "all adults", so both age fields are empty. The adult schedule adds two rows this sentence does not cover: one dose of Tdap in each pregnancy, and one dose of Td or Tdap for wound management.
CDC recommends 2 doses of recombinant zoster vaccine (RZV) to prevent shingles and related complications in adults aged ≥50 years.
Our note: The same page adds a second population the age row does not cover: 2 doses of RZV for adults aged 19 years and older who are or will be immunodeficient or immunosuppressed because of disease or therapy. It also states that a prior episode of shingles, a prior dose of the discontinued Zostavax, and the absence of a documented chickenpox history all make no difference to the recommendation.
CDC recommends pneumococcal vaccination for children younger than 5 years and adults 50 years or older.
Our note: The quoted sentence covers children as well as adults; only the adult clause is used here, and the population cell says so. The adult instruction on the same page reads: "Administer PCV15, PCV20, or PCV21 for all adults 50 years or older" who have never received a conjugate vaccine or whose history is unknown. If PCV15 is used, a dose of PPSV23 follows one year later; if PCV20 or PCV21 is used, no PPSV23 dose is indicated. Adults under 50 with risk conditions are covered by a separate risk-based row.
The Advisory Committee on Immunization Practices (ACIP) recommends hepatitis B (HepB) vaccination among all infants at birth, unvaccinated children younger than 19 years of age, adults aged 19–59 years, and adults aged 60 years and older with risk factors for hepatitis B or without identified risk factors but seeking protection.
Our note: No stop age is set because the recommendation does not close at 59: adults 60 and older are covered both with risk factors and, on request, without them. The number of doses comes from the adult schedule's own hepatitis B row, which reads "2, 3, or 4 doses depending on vaccine or condition".
Vaccination is not recommended for everyone older than age 26 years. Some adults ages 27 through 45 years might decide to get the HPV vaccine based on discussion with their clinician, if they did not get adequately vaccinated when they were younger.
Our note: Routine HPV vaccination runs through age 26 and can be started at 9; this row covers the band above it, which is the one that concerns most readers of this page. The page states its reason for the weaker position: "HPV vaccination of people in this age range provides less benefit, for several reasons, including that more people in this age range have already been exposed to HPV."
Part of that ongoing work is to maintain our childhood and adult vaccine schedules, which have just been updated for 2026.
Our note: From the AAFP Chief Medical Officer's post announcing the 2026 schedules. DATE: the page's own publish-date element reads March 24, 2026, which is used; a second dateline, April 24, 2026, is bolded lower on the page, and the earlier of the two is taken. NO AGES AND NO INTERVAL are entered because the quoted sentence states none; AAFP's adult schedule covers ages 19 and older but that is stated on a different, undated page. That page also says: "This version of the adult immunization schedule has been adopted by the American Academy of Family Physicians (AAFP)."
Although the American Academy of Family Physicians (AAFP) has usually endorsed the immunization schedule published by the Centers for Disease Control and Prevention (CDC), which is typically based on the recommendation of the Advisory Committee of Immunization Practices (ACIP), the AAFP published its own 2025 recommendations with a few substantive differences.
Our note: From American Family Physician 2026;113(1):98-99, the page stating "This article was updated on January 15, 2026", the date used. No ages and no interval are stated for this position, so those cells are empty. On the ADULT schedule specifically, AAFP's own adult schedule page says: "The CDC's 2025 immunization schedules, which are not endorsed by the AAFP, can be found here." That page carries no publication date, which is why it is quoted here rather than used as a dated row of its own.
Routine pneumococcal vaccination is now recommended at 50 years of age rather than the previous recommendation of 65 years.
Our note: Listed under Key Points for Practice. This is a row where AAFP and CDC agree, and it is the change most likely to affect a reader in their fifties: the threshold moved down from 65. The quoted sentence gives no dose schedule, so the interval cell is empty; the doses are on the CDC pneumococcal row above. Same source and date convention as the row above.
Why they differ
For most of the last two decades there was nothing to compare here: CDC published the adult schedule, AAFP endorsed it, and that was the answer. That stopped, and both parts of what replaced it are worth knowing.
1. The federal schedule currently in force is not the one the agency last published. CDC's own adult schedule page states that, pursuant to a preliminary order issued on March 16, 2026 in American Academy of Pediatrics et al. v. Kennedy et al., which stayed all votes taken by ACIP during its June, September and December 2025 meetings and further stayed the Acting CDC Director's January 5, 2026 Decision Memo, the schedule posted is the July 2, 2025 one, amended on April 27, 2026 to add an RSV recommendation. A reader comparing two summaries written months apart can therefore find genuinely different federal schedules, both accurately reported at the time.
2. AAFP no longer endorses CDC's schedule, and says so on the page. Its adult schedule page carries the line "The CDC's 2025 immunization schedules, which are not endorsed by the AAFP, can be found here." American Family Physician states the reasoning: AAFP "has usually endorsed" the CDC schedule, and published its own with "a few substantive differences". (That article also carries an editorial note saying CDC recommendations "were issued through a nondeliberative process and have not been endorsed by the American Academy of Family Physicians or the American Academy of Pediatrics", but its preceding sentence scopes it to "the childhood immunization schedule", so it is not evidence about the adult schedule and is not used as such here. The adult non-endorsement is the sentence quoted above, from AAFP's own adult schedule page.)
AAFP also publishes how its schedule is now made, which is the part that explains why the two can diverge at all: "the AAFP's Commission on Health of the Public and Science each year analyzes recommendations from the CDC's Advisory Committee on Immunization Practices and the U.S. Preventive Services Task Force, as well as the latest science and evidence. Our analysis this year included other data sources in addition to these usual sources before the recommendations went to the Board of Directors for a final determination."
Two practical points. The published differences are concentrated in pediatric and pregnancy COVID-19 vaccination, not in the adult rows a 40-year-old cares about: AAFP recommends COVID-19 vaccination during pregnancy where CDC recommends shared clinical decision-making. And on the adult rows themselves the two agree, including the pneumococcal threshold moving from 65 to 50. If your clinician is a family physician, the schedule on their wall may be AAFP's rather than CDC's, and for most adult vaccines that changes nothing.
What the test involves
An injection, almost always in the upper arm, usually at a primary-care visit or a pharmacy. Several can be given on the same day at different sites: CDC states that recombinant and adjuvanted vaccines such as Shingrix can be administered concomitantly at different anatomic sites with other adult vaccines, including COVID-19 vaccines.
Neither schedule is read by age alone. Both publish a second table organized by medical condition and other indication, and both instruct clinicians to check it after the age table, then read the notes for dosing intervals and special situations.
If the result is abnormal
Doses are recorded, and the record is what the next clinician works from. If a series is interrupted, CDC's rule for the shingles vaccine is the general pattern: give the missed dose as soon as possible and do not restart the series.
Two rows on the adult schedule repeat forever rather than finishing: influenza, annually, and the tetanus, diphtheria and pertussis booster, every ten years. Everything else on the age table is a finite series, though several are re-opened by a new medical condition, a pregnancy, or an injury.
More on this screening
Frequently asked questions
Which schedule should I follow, CDC's or AAFP's?
For the adult rows they agree, so in practice it rarely matters. The published differences between the two are concentrated in pediatric COVID-19 vaccination and COVID-19 vaccination in pregnancy. If you want to know which one your clinician is using, ask: AAFP's page says its version has been adopted by the AAFP and that CDC's 2025 schedules are not endorsed by the AAFP.
I am 52. What is new for me?
Two rows open at 50. Pneumococcal vaccination is now recommended from 50 rather than 65, which both bodies state. Shingles vaccination is 2 doses of recombinant zoster vaccine, 2 to 6 months apart, from 50, whether or not you have had shingles before and whether or not you remember having chickenpox. RSV vaccination opens at 50 with risk factors on the current federal schedule, and at 75 for everyone.
Do I need an HPV vaccine at 40?
Probably not, and CDC says so plainly: vaccination is not recommended for everyone older than 26. Between 27 and 45 it is a discussion with your clinician rather than a routine recommendation, because more people in that age range have already been exposed to HPV, so the benefit is smaller.
When was my last tetanus booster meant to be?
Every 10 years, per CDC, for all adults. Once you have had one dose of Tdap, later boosters can be Td or Tdap. A dirty or deep wound can bring the next one forward regardless of when the last one was.